Tamsulosin CAS NO.106133-20-4

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Tamsulosin CAS:106133-20-4

1.Product profile

Product name: Tamsulosin

CAS No.: 106133-20-4

MF: C20H28N2O5S

Purity: 99.5% min

Molecular Weight:408.5117

2.Speficication

ITEM TESTED			STANDARD	RESULTS
characteristics			White or almost white crystalline powder	Almost white crystalline powder;
			Slight soluble in water, freely soluble in formic acid	Odorless and tasteless ;
			Slightly soluble in anhydrous ethanol	the product meets the requirement of test for solubility
Melting point			About 230 °C	233.1-233.5°C
identification			1)should conformed	1) Conform
			2)Specific rotation: between -17.5 and -20.5 °	2) -19.0°
			3) Examine by infrared absorption spectrophotometry, compare the spetrum obtained with reference spectrum: should meet the requirement	3) Conform
			4)Should conformed	4) Conform

Test
Related substances		Procedure A: Largest single impurity should no more than 0.1%		0.024%
		Procedure B Largest single impurity should no more than 0.1% Total impurity should no more than 0.2%		0.001% 0.019%
Enantiomeric purity		No more than 0.1%		0.024%
Heaxy metals		No more than 20ppm		conform
Loss on drying		No more than 0.5%		0.03%
Sulphated ash		No more than 0.1%		0.02%
Residual solvent	Ethanol	No more than 5000ppm		400ppm
assay		Should between 98.5% and 101.0 per sent		99.4%
The material complies with respect to EP 7.0

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