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Home > Products >  Rosiglitazone maleate

Rosiglitazone maleate CAS NO.155141-29-0

  • FOB Price: USD: 100.00-100.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,T/T,
  • Available Specifications:

    1(1-5)Kilogram1(5-10)Kilogram2(10-50)Kilogram

  • Product Details

Keywords

  • 5-{p-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-
  • Rosiglitazone maleate price
  • Rosiglitazone maleate factory

Quick Details

  • ProName: Rosiglitazone maleate
  • CasNo: 155141-29-0
  • Molecular Formula: C22H23N3O7S
  • Appearance: White or almost white,crystalline powd
  • Application: APIs
  • DeliveryTime: 3--5 days
  • PackAge: Packing according to the arrangement
  • Port: Shanghai,Guangzhou,Qingdao,Tianjing,Sh
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 99.8%
  • Storage: Kept in a well-closed, light-resistant...
  • Transportation: by sea or by air
  • LimitNum: 1 Kilogram
  • Related Substances: Rosiglitazone
  • Residue on Ignition: maleate
  • Heavy Metal: [2-(Methyl-2-pyridylamino)ethoxy]benzy...
  • Valid Period: 02/7/2020
  • White or almost white,crystalline powd: Kept in a well-closed, light-resistant

Superiority

Superiority

1.Shaanxi Top Pharm Chemical Co., Ltd., is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates in China.

2. The yearly production capacity is 50000MT, 80% for export.We have a professinal export team. Both by Air and by Sea,we ensure that we meet the customer expectations with promptness.
3. Our company facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service.
4. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.

 

Details

Details

Detailed Product Description
Rosiglitazone maleate
Synonyms: 5-((4-[2-(METHYL-2-PYRIDINYLAMINO)-ETHOXY]-PHENYL)-METHYLENE)-2,4-THIAZOLIDINEDIONE;5-{p-[2-(methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedione maleate;ROSIGLITAZONE MALEATE;RosiglitazoneTartrate;Avandi;BRL-49653c;RSIGLITAZONEMALEATE;5-(4-(2-(Methyl(pyridin-2-yl)aMino)ethoxy)benzyl)thiazolidine-2,4-dione Maleate
CAS: 155141-29-0
MF: C22H23N3O7S
MW: 473.5
Chemical Properties White To Off-White Solid
Usage Insulin sensitizer; binds to peroxisome proliferator activated receptor gamma (PPAR- γ).
Usage Thiazole alkanes antidiabetic drug
Package: 25kg/drum
Standard: enterprise Standard
Lead Time: Within 24 hours after receiving the payment
Delivery time:4-6 working days by Air for quantity less than 200kgs or 20 days By sea for quantity over than 250kg.
Certificates: ISO9001
Payment terms: , Money Gram, T/T


Rosiglitazone is a thiazolidinedione insulin sensitizer that activates PPARγ, decreasing blood glucose and insulin levels. Rosiglitazone exhibits anti-diabetic, anti-inflammatory, antioxidative, anticancer, anti-angiogenic, antihypertensive, and anti-fibrotic activities. In vivo, rosiglitazone decreases LPS-stimulated production of TNF-α, IL-1β, and IL-6 as well as activity of myeloperoxidase; it also inhibits activation of NF-κB, preventing mastitis. In multiple myeloma cells, rosiglitazone suppresses expression of HIF-1α and IGF-1, decreases activation of Aky, and Erk, and inhibits cell viability and proliferation. This compound also inhibits endothelin-1-induced vasoconstriction in a NO-dependent manner in animal models of pulmonary arterial hypertension. Additionally, rosiglitazone prevents activation of AP-1, production of collagen, and differentiation in fibroblasts.

 

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