China (Mainland)
Amlodipine besilate CAS NO.111470-99-6
- FOB Price: USD: 100.00-100.00 /Kilogram Get Latest Price
- Min.Order: 10 Kilogram
- Payment Terms: L/C,D/A,T/T,Other
- Available Specifications:
USP/EP(10-1000)Kilogram
- Product Details
Keywords
- Amlodipine besilate
- 111470-99-6
- White crystalline powder
Quick Details
- ProName: Amlodipine besilate
- CasNo: 111470-99-6
- Molecular Formula: C26H31ClN2O8S
- Appearance: White crystalline powder
- Application: API
- DeliveryTime: Prompt shipment
- PackAge: As your needed
- Port: any port in China
- ProductionCapacity: 20 Metric Ton/Week
- Purity: >99%
- Storage: room temperature
- Transportation: SEA AIR
- LimitNum: 10 Kilogram
- Impurity: POWDER
- Syntheses Material Intermediates: White Crystalline Solid
Superiority
1, Full experience of large numbers containers loading in main Chinese seaports
2, Packing with pallet as buyer's special request
3, Best service after shipment with e-mail
4, Cargos together with container sales seervice available
5, Rich experience for exporting
6, Cargos photo before and after loading into container
7, Raw materials from chinese origin
8, Top Pharm Chemical Group(ISO 9001: 2008), are strong in the field of Pharmaceuticals,
food additives, plant extract and fine chemicals for more than 10 years.
Details
| Amlodipine besilate Basic information |
| Product Name: | Amlodipine besilate |
| Synonyms: | 2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE;2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate;AMLODIPINE BENZENESULFONATE;AMLODIPINE BESILATE;AMLODIPINE BESYLATE;NORVASC;3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,;4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate |
| CAS: | 111470-99-6 |
| MF: | C26H31ClN2O8S |
| MW: | 567.05 |
| EINECS: | |
| Product Categories: | Active Pharmaceutical Ingredients;Dihydropyridine Class Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Amlodipine;Aromatics;Dihydropyridine;Heterocycles;BENICAR |
| Mol File: | 111470-99-6.mol |
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| Amlodipine besilate Chemical Properties |
| mp | 199-201°C |
| storage temp. | Store at RT |
| solubility | DMSO: 20 mg/mL |
| form | solid |
| color | white |
| CAS DataBase Reference | 111470-99-6(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38-20/21/22 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | US7967700 |
| Hazardous Substances Data | 111470-99-6(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Amlodipine besilate Usage And Synthesis |
| Chemical Properties | White Crystalline Solid |
| Usage | A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive |
| Usage | Angiotensin II inhibitor prodrug, antihypertensive |
| Usage | Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats. |
| Biological Activity | L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC 50 = 25 μ M). |
| Amlodipine besilate Preparation Products And Raw materials |
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