Orlistat cas:96829-58-2 CAS NO.96829-58-2
- FOB Price: USD: /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
USP/EP(1-100)KilogramUSP/EP(100-1000)Kilogram
- Product Details
Keywords
- Orlistat
- cas:96829-58-2
- Orlipastat
Quick Details
- ProName: Orlistat cas:96829-58-2
- CasNo: 96829-58-2
- Molecular Formula: C29H53NO5
- Appearance: White crystalline powder
- Application: API for loss weight
- DeliveryTime: in 7 -25 days
- PackAge: 25Kg/drum,5KG/Aluminum foil bag,1KG/Al...
- Port: Shanghai Dalian Tianjing Beijing
- ProductionCapacity: 10 Metric Ton/Month
- Purity: ≥98%
- Storage: keep in cool and dried place
- Transportation: by sea/air
- LimitNum: 1 Kilogram
- Related Substances: ≤0.5 %
- Residue on Ignition: ≤0.1%
- Heavy Metal: ≤20ppm
- Valid Period: 2 years
Superiority
Details
Test Items | Specifications |
Specific Rotation | -48° ~ -51.0°(on the anhydrous, solvent-free basis) |
Identification | A.HPLC: The retention time of the major peak of the sample solution corresponds to that of the standard solution. |
B.IR: The IR spectrum of sample is consistent to the reference | |
Related Substances | |
Total impurity | Not more than 1.0% |
Related Compound A | Not more than 0.2% |
Related Compound B | Not more than 0.05% |
Related Compound C | Not more than 0.05% |
Related Compound D | Not more than 0.2% |
Related Compound E | Not more than 0.2% |
Formyl leucine | Not more than 0.2% |
Orlistat open ring epimer | Not more than 0.2% |
D-Leucine orlistat | Not more than 0.2% |
Orlistat open ring amide | Not more than 0.1% |
Individual unidentified impurity | Not more than 0.1% |
Residual Solvents | |
n-Hexane | Not more than 5000ppm |
Isopropyl ether | Not more than 5000ppm |
Residual on ignition | Not more than 0.1% |
Heavy Metal | Not more than 20ppm |
Water | Not more than 0.2% |
Assay | 98.0%~101.5% (on the anhydrous, solvent-free basis) |
Conclusion | Conform with USP35 |
Orlistat is used for the treatment of obesity.The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body mass.After orlistat was stopped, a significant number of subjects regained weight—up to 35% of the weight they had lost.
The incidence of type 2 diabetes in an obese population over four years is decreased with orlistat (6.2%) compared to placebo (9.0%).Long-term use of orlistat also leads to a modest reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).
Top Pharm Chemical Group is a regional, research ,industry and trade of hightech pharmaceutical chemical group .Headquartered in JiuLong Hong Kong . In recent years, through continuous integration, mergers and establish three domestic production base , now has its TOP Hanzhong plant extract production base , production base TOP Xi'an food additives , chemical intermediates production base TOP Taizhou .And China Marketing Center : Shaanxi TOP Pharm Chemical Co., Ltd. Sole responsibility for the TOP Group of each base , raw material supply factories , sales and import and export business ,providing thousands of plant extracts , food additives , feed additives , vitamin , pharmaceutical raw materials (API), chemical intermediates and other related customers worldwide products.
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